![]() ![]() Furthermore, a detailed analysis in the state-of-the-art use of microfluidics within biotechnology was conducted exemplarily for four emerging biotechnological fields that can substantially benefit from the application of microfluidic systems, namely the phenotypic screening of cells, the analysis of microbial population heterogeneity, organ-on-a-chip approaches and the characterisation of synthetic co-cultures. ![]() In this review, we highlight microfluidics' offers and compare them to the most important demands of the biotechnologists. For many years, absent innovative, groundbreaking and "out-of-the-box" applications have been made responsible for the missing drive to integrate microfluidic technologies into fundamental and applied biotechnological research. ![]() Although microfluidic tools were increasingly used for different applications within biotechnology in recent years, a systematic and routine use in academic and industrial labs is still not established. Microfluidics and novel lab-on-a-chip applications have the potential to boost biotechnological research in ways that are not possible using traditional methods.
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